منابع مشابه
Rapid diagnostic HCV antibody assays.
Approximately 4.1 million Americans have been infected with HCV and 45-85% of chronically infected persons are unaware of their status. Rapid anti-HCV assays can assist and expedite the identification of those unaware of their infection. Performance characteristics of pre-market rapid anti-HCV assays (Chembio, MedMira and OraSure) have been evaluated. Their sensitivity (78.9-99.3%) and specific...
متن کاملThe Diagnostic Sensitivity of Dengue Rapid Test Assays Is Significantly Enhanced by Using a Combined Antigen and Antibody Testing Approach
BACKGROUND Serological tests for IgM and IgG are routinely used in clinical laboratories for the rapid diagnosis of dengue and can differentiate between primary and secondary infections. Dengue virus non-structural protein 1 (NS1) has been identified as an early marker for acute dengue, and is typically present between days 1-9 post-onset of illness but following seroconversion it can be diffic...
متن کاملDiagnostic Assays for Infectious
Validation is a process that determines the fitness of an assay, which has been properly developed, 6 optimised and standardised, for an intended purpose. Validation 8 includes estimates of the analytical and diagnostic performance 10 characteristics of a test. In the context of this chapter, an assay that 12 has completed the first three stages of the validation pathway (see 14 Figure 1 below)...
متن کاملPoor diagnostic accuracy of commercial antibody-based assays for the diagnosis of acute Chikungunya infection.
A Sri Lankan fever cohort (n = 292 patients; 17.8% prevalence) was used to assess two standard diagnostic Chikungunya IgM tests. The immunochromatographic test (ICT) acute sample sensitivity (SN) was 1.9 to 3.9%, and specificity (SP) was 92.5 to 95.0%. The enzyme-linked immunosorbent assay (ELISA) gave an acute sample SN of 3.9% and an SP of 92.5% and a convalescent sample SN of 84% and an SP o...
متن کاملDiagnostic assays for anti-PM/Scl IgG antibodies: heterogeneity in antibody response or lack of standardization?
BACKGROUND The aim of this study was to compare the correlation between new diagnostic methodologies for detecting anti-polymyositis/scleroderma (anti-PM/Scl) IgG antibodies associated with myositis and/or systemic scleroderma assays with existing platforms. METHODS Sera from 164 samples previously tested for anti-PM/Scl IgG antibody by immunodiffusion, ID; 171 sera screened for anti-PM/Scl I...
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ژورنال
عنوان ژورنال: Antiviral Therapy
سال: 2012
ISSN: 1359-6535
DOI: 10.3851/imp2470